Yankees 8, Red Sox 0

NEW YORK — James Paxton struck out 12 in his first stab at baseball’s biggest rivalry, Red Sox ace Chris Sale found his fastball but not better results, and the New York Yankees three-hit Boston 8-0 on Tuesday night in the first game this season between the struggling AL East foes.

Paxton (2-2) pitched two-hit ball for eight innings, walking one and going to just two three-ball counts in a game that took only 2 hours, 23 minutes.

Mike Tauchman hit his first major league homer and drove in four runs, and Clint Frazier and Gleyber Torres also went deep for the Yankees. New York had dropped five of six and is 7-9 a year after winning 100 games.

Sale (0-4) reached 97.5 mph — a positive sign for Boston after his velocity sagged this spring — but still got hit around, allowing four runs and seven hits over five innings. He struck out six and walked one while the World Series champions dropped to 6-12.

Pirates 5, Tigers 3, (10)

DETROIT — Starling Marte hit a two-run homer in the 10th inning to lift Pittsburgh over Detroit.

Jung Ho Kang also went deep for Pittsburgh, which blew a 3-0 lead but recovered to win when Marte hit a two-out drive off Shane Greene (0-1). Detroit’s closer hadn’t allowed a run all season.

Keone Kela (1-0) gave up a tying single by Jeimer Candelario in the ninth, but Nick Kingham was able to close out the Tigers in the 10th for his first career save.

Pittsburgh starter Joe Musgrove permitted his first two earned runs of the season. He yielded six hits and a walk while striking out six in seven innings.

Phillies 14, Mets 3

PHILADELPHIA — Scott Kingery and J.T. Realmuto each had three hits and five RBIs as Philadelphia routed New York.

Kingery and Maikel Franco hit three-run homers and Realmuto had a pair of two-run doubles in a 10-run first inning. Realmuto also went deep for the Phillies in the fourth.

Nick Pivetta (2-1) gave up three runs and seven hits in five innings.

Giants 7, Nationals 3

WASHINGTON — Evan Longoria, Brandon Belt and Steven Duggar homered off fastballs from Stephen Strasburg and light-hitting San Francisco powered past Washington.

The Giants entered the game with 10 homers through their first 17 games. They won for the fourth time in five games.

Astros 9, Athletics 1

OAKLAND — Alex Bregman hit a grand slam, Josh Reddick connected for a two-run homer against his former team, and Houston beat Oakland for their majors-best 10th straight win.

Bregman’s second career grand slam gave Collin McHugh (3-1) all the run support he needed on the way to winning his third straight start. Bregman’s other slam came May 14, 2017, at the Yankees.

Cubs 4,  Marlins 0

MIAMI — Jose Quintana gave up six hits in seven innings to lead Chicago over Miami.

Quintana (2-1) struck out seven and extended his scoreless innings streak to 14. He didn’t allow a runner to reach second until Austin Dean’s two-out double in the seventh.

Rays 4, Orioles 2

ST. PETERSBURG, Fla. — Tyler Glasnow allowed two runs over seven innings in winning his fourth consecutive start to begin the season and Avisail Garcia drove in three runs as Tampa Bay beat Baltimore for its seventh win in eight games.

Glasnow (4-0) allowed hits to six of the first 13 batters, but allowed one hit over his final 4 2/3 innings and ended the outing by retiring 10 in a row.

Diamondbacks 9, Braves 6

ATLANTA — Christian Walker homered leading off the ninth inning and Arizona rallied against the shaky Atlanta bullpen. The Braves squandered a massive, knee-buckling homer by Ronald Acuña Jr. and another strong start by Max Fried.

Blue Jays 6, Twins 5

MINNEAPOLIS — Teoscar Hernandez and Justin Smoak hit two-run singles as Toronto rallied past Minnesota.

Hernandez singled off Twins reliever Trevor Hildenberger in the top of the seventh to give Toronto a 6-4 lead. Hernandez had capitalized against Minnesota’s bullpen a day earlier, too, hitting a home run in the eighth inning that gave the Blue Jays a 5-3 win Monday.

Brewers 8, Cardinals 4

MILWAUKEE — Christian Yelich hit a three-run homer, his eighth against St. Louis this season, to help send Milwaukee to the win.

Lorenzo Cain and Yasmani Grandal each homered in a five-run third against Jack Flaherty (1-1), when the Brewers went up 5-0.

White Sox 5, Royals 1

CHICAGO — Yoan Moncada hit a pair of solo shots for his first multihomer game and Leury Garcia added a two-run drive to power Chicago past Kansas City.

Rockies 8, Padres 2

SAN DIEGO — Nolan Arenado homered for the third straight game — a two-run shot on his 28th birthday — and Jon Gray pitched seven strong innings as Colorado beat San Diego for a two-game sweep and its first three-game winning streak of the season.

Indians 4, Mariners 2

SEATTLE — Shane Bieber struck out five and combined with three relievers to hold Seattle to six hits as Cleveland beat the Mariners and stretched their winning streak to three games.

The Mariners extended their major league record home-run streak to start the season to 20 games. 

Seattle now has 42 home runs, yet is mired in a five-game losing streak after a stretch of six straight wins that once had the Mariners atop the standings.

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